Michael Tattory

Bay Area Researchers Key on Blood Plasma to Fight Age-Related Diseases

A year ago, the FDA issued a warning to consumers to stay away from unscrupulous clinics that offered blood taken from young people to use as an anti-aging remedy. But one Bay Area biotech company is actually gathering the scientific evidence and conducting well-designed studies, under the approval of the FDA.

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Reversing Disease Signals by The Bio Report

Ben Zeskind likens Immuneering’s platform technology to noise-cancelling headphones. Infact, the company’s use of the term “Disease Cancelling Technology” speaks directly to that. The approach, he says, allows the company to build a pipeline of drug candidate that address aspects of disease that have eluded tradition drug development approaches. We spoke Zeskind, CEO of Immuneering,

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Synaptive Medical updates Modus V surgical microscope

Synaptive Medical announced that its U.S. and Canadian Modus V robotic digital microscope now includes updates such as additional 3D visualization and voice-activated control. The Modus V is a robotically controlled digital microscope used as part of Synaptive’s BrightMatter surgical suite designed for less invasive, patient-specific approaches in complex cranial procedures.

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NantKwest Gains 91% After Promising Cancer Result

NantKwest Inc. shares rose by a record after the company’s CEO said its experimental cancer therapy had shown a dramatic result in one patient with pancreatic cancer. In an interview with Bloomberg Television, Chief Executive Office Patrick Soon-Shiong said one patient with metastatic pancreatic cancer had their tumors eradicated after treatment with the company’s experimental

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empowered

Targeting Specific Proteins to Treat Triple Negative Breast Cancer with Usama Malik Immunomedics

Usama Malik, Chief Financial Officer and Chief Business Officer, Immunomedics discusses the challenges of developing effective medicines for people with triple negative breast cancer as well as Immunomedics’ development of antibody-drug conjugates, directed therapies which have potential to provide new options for those with hard to treat cancers.

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Nurix, Sanofi in protein degradation deal

Nurix Therapeutics Inc. and Sanofi partnered to develop protein degradation therapies for three targets and multiple diseases. Sanofi, which has an option to license compounds for two additional targets, has exclusive rights to the candidates and is responsible for clinical development and commercialization. Nurix, which has a co-development and co-promotion option to up to two

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Led by Blatt, Aligos reunites Alios team to develop functional cure for HBV

Led by a team of veterans from Alios BioPharma and Janssen, Aligos Therapeutics raised $125 million in a series B round to bring three of its HBV therapies to the clinic this year. Aligos thinks that in combination, the trio of modalities could lead to the development of a functional HBV cure under one roof.

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Small Biotech Often Better Suited to Develop Rare Disease Therapies

Gaurav Shah, MD, Chief Executive Officer & President of Rocket Pharmaceuticals explains the advantages that smaller biotech companies have in developing treatments for rare diseases. Rocket Pharmaceuticals is currently developing gene therapies for a number of rare conditions, including Fanconi anemia, Danon disease, leukocyte adhesion deficiency-I, pyruvate kinase deficiency, and infantile malignant osteopetrosis.

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Harnessing the Body’s Own Protein Waste Removal System to Drug the ‘Undruggable’

How do you catch just one kind of fish in a sea of similar fish? That’s the question being answered by researchers at Nurix, except they aren’t catching fish – they are ‘catching’ proteins in your body. Nurix is developing drugs that can specifically target one protein within the hundreds or thousands of extremely similar

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Check-Cap’s Swallowable X-Ray Pill Allows For Prep-Free Colon Cancer Screenings

It’s no secret that preparation for a colonoscopy is an uncomfortable experience. At times, the preparation can be so off-putting, that some chose to forgo the procedure altogether. For this reason, Check-Cap has created an indigestible capsule for prep-free colon cancer screening to ensure that no patient gets left behind in cancer precaution. The device

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Takeda taps brain-focused Cerevance in quest for new GI targets

Three years after Takeda chipped into Cerevance’s series A, the Big Pharma has come back for more. The duo is inking a research deal focused on identifying new protein targets in the central nervous system to develop new treatments for gastrointestinal disorders. The companies kept details close to the vest but said Cerevance could net

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Developing A Smart Inhaler For Optimal Drug Delivery

Historically, inhalation drug delivery was limited to the treatment and management of respiratory diseases, such as asthma or chronic obstructive pulmonary disease. However, this delivery approach has broadened as an alternative treatment option for a number of systemic diseases,[i] including endocrine and neurological diseases, which could benefit from the frequent pulsatile administration afforded by an

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Cleveland company developing technology to help patients with diabetes

As the cost of life-saving insulin soars for people with diabetes, a Cleveland company is developing nanotechnology that could help. The technology, from Diasome, makes insulin more effective in the body so less is needed to regulate blood sugar. Insulin costs for patients with type one diabetes doubled between 2012 and 2016, according to the

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Bucks County medical device firm lands $20M credit deal from Silicon Valley Bank

Bucks County medical device company Orchestra BioMed said Tuesday it has entered into a $20 million credit agreement with Silicon Valley Bank. This deal provides Orchestra BioMed with an initial amount of up to $10 million it can use for development and general corporate expenditures during the next 12 months. The remaining will be available to the

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IPO Window, Recession, Trade War & More — 5 Biopharma Finance Experts Share Their Perspectives For 2020

We are always acutely aware of investors’ appetite to participate in financing deals, and to what degree. There has been a lot of chatter about the “window closing” in 2020, but from what we can see, financing deals for good science and novel ideas are still getting done, and we’re cautiously optimistic that the environment

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Pfizer, Novartis lead $2 billion spending spree on gene therapy production

Eleven drugmakers led by Pfizer and Novartis have set aside a combined $2 billion to invest in gene therapy manufacturing since 2018, according to a Reuters analysis, in a drive to better control production of the world’s priciest medicines. The full scope of Novartis’ (NOVN.S) $500 million plan, revealed to Reuters in an interview with

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ProQR: Developing RNA Therapies for Rare Genetic Disorders

There is a great need for transformative treatments that increase life expectancy and improve the quality of life of patients and families living with rare inherited diseases. Current therapeutic approaches, including small molecules and enzyme replacement therapies, have limitations and cannot be applied to every disease. ProQR specializes in the development of RNA therapies and

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“Squeezing” Cells Could Transform Cell Therapy Manufacturing

Manufacturing today’s cell therapies remains expensive and complex due to the need for viruses or electric shocks to engineer patient cells. Yescarta®, for example, one of the first CAR-T therapies approved for sale, takes 3-4 weeks to reach patients and has a price tag of $373,000.00. With CAR-T, expanding out a patient’s T-cells and transducing them with

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