Tolerogenic Therapies Retrain the Immune System
COUR Pharmaceuticals’ emerging platform reprograms the immune system to address the root causes of autoimmune diseases
Tolerogenic Therapies Retrain the Immune System Read More »
COUR Pharmaceuticals’ emerging platform reprograms the immune system to address the root causes of autoimmune diseases
Tolerogenic Therapies Retrain the Immune System Read More »
With LB Pharmaceuticals, Turner “liked the fact that it’s a very focused neuropsych company; this is where we’re going. And I also liked the fact that there was a near-term catalyst with our Phase 2 clinical program.” In other words, the company had a clear strategy in place; all it needed was a leader who
A CEO With A General Counsel’s Perspective Read More »
Last year, Tessera Therapeutics’ CEO, Dr. Michael Severino, was my guest on Cell & Gene: The Podcast to discuss Gene Writing, the biotech’s genome
Tessera Therapeutics Advances In Vivo Gene Therapy For SCD Read More »
Chicago Biomedical Consortium and COUR Pharmaceuticals executives share what makes the area a hot spot.
Chicago Area’s Life Sciences Scene Continues Making an Impression Read More »
A private startup looking to bring an old schizophrenia drug class to the US has released new Phase 2 data and aims to start a …
LB Pharmaceuticals has shared top-line data from a phase 2 schizophrenia trial, touting results that offer early support for its vision and putting it on track to start a pivotal study around the end of the year.
LB Pharma’s twist on old Sanofi drug passes schizophrenia test, teeing up phase 3 push Read More »
MindMed announced the first patient had been dosed in the first-ever phase 3 trial of lysergic acid-diethylamide (LSD) for generalized anxiety disorder (GAD). MindMed is currently the furthest along in clinical trials exploring LSD as a treatment in multiple psychiatric indications, including major depressive disorder.
COUR Pharmaceuticals has been, as its newly-appointed President & CEO Dannielle Appelhans puts it, flying under the radar for a long time. COUR made a splash back in 2015, when it formed up around a biodegradable nanoparticle encapsulating gliadin proteins that proved to reverse the effects of gluten in animal models.
Internalizing Nanoparticle Therapeutic Development Read More »
V.P. of R&D Tim Culp describes the rationale for in vivo CAR programs, what the company will be watching for from a safety standpoint, the development path ahead, and competition.
President-elect Donald Trump and Robert Kennedy, Jr. — his pick to head up the Department of Health and Human Services — were hot topics at the Jefferies …
Doctor Peter Vanderklish from Spinogenix talks about their advanced human trials in synaptic generation. Doctor Vanderklish, welcome to the program.
Rewiring the Brain… Dr. Peter Vanderklish, Chief Scientific Officer, Spinogenix Read More »
CEO Rajesh Devraj describes the company’s focus on membrane protein function and normalizing it with small molecules, in this case for cholestasis and cholangitis associated with liver diseases.
CEO Berndt Modig describes the science behind creating both immediate release capsuls and extended release tablets. Successfully developing an oral therapy could set Pharvaris apart.
While Anima has contributed to the scientific literature itself, with a growing list of peer-reviewed publications on protein synthesis monitoring and tRNA visualization, Slonim argues that relying solely on mining existing research isn’t enough.
Industry leaders reshaping the pharma world.
The 2024 PharmaVoice 100 Read More »
From a trial design perspective, we’ve tried to make these trials as familiar to stakeholders – regulators, prescribers, payors – as possible. What’s remarkable here are the qualities of the drug that we’re developing, MM120, a pharmaceutical formulation of LSD; we don’t need to do anything inconsistent with the history of psychiatric clinical trials beyond
Pharvaris is moving forward with Phase 3 clinical trials. The RAPIDe-3 study (NCT06343779) is testing an immediate-release formulation of deucrictibant, called PHVS416, as an on-demand therapy for HAE. Recruitment is ongoing at sites in the U.S., Puerto Rico, South Korea, and Germany.
Data show sustained benefits of deucrictibant for HAE attacks Read More »
Revolo Biotherapeutics’ CEO, Woody Bryan, discusses how ‘1104, the Company’s lead candidate for allergic diseases, shifts the immune system from a pro-inflammatory state to a homeostatic state, offering potential remission for allergic conditions.
’1104: tackling the root cause of allergic disease Read More »
At the World AMR Congress, Recce Pharmaceuticals contributes by making strides with a synthetic compound designed to target bacterial mutations, underscoring the need for innovation in addressing antimicrobial resistance (AMR). “Our compound is entirely synthetic,” Graham said. “We started with first principles, designing a compound that remains effective with repeated use.”
Recce Pharmaceuticals Advances Antibiotic Development to Combat Antimicrobial Resistance Read More »
This conversation features Dr Philipp Spycher, CSO and co-founder at Araris Biotech, and Dr Rebecca Boohaker, Director of Oncology at Southern Research.
Combatting disease with antibody drug conjugates Read More »
Biotech company MindMed is shoring up its cash stockpile to inch its psychedelic therapies towards approval after the feds’ recent thumbs-down of using MDMA to treat post-traumatic stress disorder.
Midtown biotech sells $75M to the public to show FDA the promise of psychedelics Read More »
Spinogenix founder Dr Stella Sarraf joined Sky News Business Editor Ross Greenwood to discuss the ongoing groundbreaking trial.
World-first MND drug trial offers hope to those living with the disorder Read More »
Pisit “Duke” Pitukcheewanont, MD, Chief Medical Officer for Lumos Pharma, discusses a phase 2 trial evaluating LUM-201 (ibutamoren) for treatment of growth hormone deficiency.
Phase 2 Trial Evaluating LUM-201 for Treatment of Growth Hormone Deficiency Read More »
Aligos is developing a capsid assembly modulator, ALG-000184, as a hepatitis B treatment. The South San Francisco, California-headquartered company presented data for the therapy at the June 2024 European Association of Liver Disease (EASL) Congress in Italy.
Hepatitis B market is ripe for treatment development, says Aligos CEO Read More »
As WHO reports a high HBV burden, Aligos Therapeutics’ CEO highlighted the potential for pharma to address unmet needs.
Hepatitis B market is ripe for treatment development, says Aligos CEO Read More »
As the inventor of the Araris ADC Technology, Philipp has a profound background in Bioconjugation and ADCs. He was the founding CEO since the inception of Araris in 2019 securing $40M in financing from Swiss, UK, US and Korean investors and $2.5M non-dilutive financing from the Swiss Accelerator Grant (5% funding rate).
Immunotherapy advancements: transforming cancer treatment Read More »
Discover how Cue Biopharma harnesses the curative potential of the body’s intrinsic immune system to develop treatments for oncology and autoimmune diseases. Here, Anish Suri, Chief Scientific Officer of Cue Biopharma, explains how its platforms and biologics are designed to selectively modulate disease-specific T cells to restore immune balance, aiming to improve efficacy and minimise
Translating ‘nature’s cues’ into breakthrough immunotherapies Read More »
The traditional approach to treating autoimmune disease has relied on ways to suppress the immune system. COUR Pharmaceuticals is developing first-in-class therapies that instead seek to reprogram the immune system to create antigen-specific tolerance. We spoke to COUR CEO John Puisis and COUR Vice President of Research Adam Elhofy, about how the company’s immune-modifying nanoparticles
Teaching Tolerance to Address Autoimmune Diseases Read More »
Zandy Forbes, Founder, President, and CEO of MeiraGTx, joins host Rahul Chaturvedi in this compelling episode. Zandy shares her inspiring journey from academia, where she developed a deep interest in molecular biology and genetics, to her significant role in biotech investing, and eventually leading a groundbreaking gene therapy company
In this post-ASCO interview with CUE Biopharma chief medical officer Matteo Levisetti, Levisetti tells pharmaphorum editor-in-chief Jonah Comstock about how his company’s tumour-specific T-cell engagers could create new opportunities for cancer immunotherapies to succeed.
ASCO 2024 – Matteo Levisetti Read More »