Olivia Vizier

8 Biotech Startup Lessons From Heat Bio’s Jeff Wolf

Any time we have an opportunity to talk with Jeff Wolf, we take it – especially when the conversation tackles the highs and lows of leading a biotech startup. Currently the founder, chairman, and CEO at the clinical-stage immuno-oncology biopharma Heat Biologics (HTBX), Wolf previously founded or co-founded Avigen, Elusys, TyRx, Generation One, and Seed

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endpoints

‘We’re not a van­t’: Ax­o­vant seeks to for­get the past as the com­pa­ny re­brands to Sio Gene Ther­a­pies

Aiming to shed the legacy of an epic Alzheimer’s fail a few years ago, Axovant $AXGT is changing its name in a full corporate rebrand. The company announced Tuesday it will now be called Sio Gene Therapies as it completes what’s been a three-year pivot away from Alzheimer’s disease and toward, well, gene therapy.

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Clover Biopharma nabs $250M-plus for COVID-19 vaccine in expanded CEPI deal

China’s Clover Biopharma is getting another boost as it gears up for a global, pivotal trial of its COVID-19 vaccine. The Coalition for Epidemic Preparedness Innovations (CEPI) is adding $258.5 million to a deal the partners initially struck in April this year, which will see the candidate through a phase 2/3 study and licensure in

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Targeting PVRIG in cancer immunotherapy

Compugen Ltd. recently presented new research data further supporting the PVRIG protein coding gene as a potentially promising target for cancer immunotherapy. These data suggest that PVRIG inhibition may enhance T cell priming and infiltration into tumors and provide further evidence supporting the potential advantages of targeting PVRIG—alone and in combination with TIGIT and PD-1 inhibitors—in

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Biotech Veteran Developing Natural Hormones for Orphan Indications

On October 14th, Amolyt Pharma announced the first dosing in its Phase I trial of AZP-3601 in healthy subjects, a momentous occasion capping off years of hard work in pre-clinical development. The drug aims to walk the biological tightrope in the management of hypoparathyroidism, a rare disease causing muscular pain and cognitive challenges.

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Execs Weigh In On Presidential Politics Impacting Biopharma

We at NeuBase have felt that there are fundamental deficiencies in the current approach to drug development. The traditional drug screening approach, which involves scouring libraries of chemicals and just seeing what works, is slow, costly, and ultimately translates to higher drug prices. We believe that there will be a revolution in the pharmaceutical industry

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Ensuring Patient-Friendly Clinical Trials For Complex Disorders — A Small Biopharma’s Playbook

Rezolute, a small company based in Redwood City, California, and working in the rare pediatric disease space, is developing a new therapeutic option specifically for patients with congenital hyperinsulinism (HI), an ultra-rare pediatric genetic disorder. For Rezolute, connecting and partnering with advocacy groups and physicians is paramount in clinical trial execution.

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