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Can gene therapy be made to work against solid tumours?

Oncosec have developed another way of delivering genes to tumour cells without the need for viral vectors or nanoparticles. They have taken advantage of the electrotransfer method used by research laboratories to transfer DNA into cells. “When you put energy through the membrane of a cell, it causes it to become porous, and if you previously surrounded that cell with DNA plasmid, once you form those pores, the plasmids will move from outside the cell, through the membrane into the cell,” explains O’Connor.