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Getting Across Tissue Barriers for Precise Delivery of Drugs with Jeff Cleland Ashvattha Therapeutics

Jeff Cleland is the Chairman, President, and CEO of Ashvattha Therapeutics, initially focusing on demonstrating the ability to deliver drugs that cross tissue barriers like the blood-brain barrier and the blood-retinal barrier to attack inflammation.

endpoints

LOW-PROFILE BIOTECH LED BY BRISTOL MYERS VETS GRABS A SUITE OF ADENOSINE RECEPTOR ANTAGONISTS VIA TINY BUYOUT

Portage Biotech — which is led by two Bristol Myers Squibb vets, CEO Ian Walters and CSO Robert Kramer — is buying out New York’s Tarus Therapeutics in a $21 million all-stock deal that gives it $3 million worth of liabilities on top of four adenosine receptor antagonists, two of which are already in Phase I/II trials.

biospace

Veru, Immunome Tout Positive Data for COVID-19 Therapeutics

Pennsylvania-based Immunome, Inc. said its antibody cocktail, dubbed IMM-BCP-01, “retained activity” against the BA.4/5 and BA.2.12.1 subvariants in pseudovirus testing.

Psychedelics Pipeline Overview: R&D Blossoms But No Panacea Among Candidates

While the psychedelic approach to mental health has recently achieved some clinical and regulatory validation, executives in the space warn the drugs cannot cure all and barriers to market remain.

BioProcessOnline

Antibody Cocktails With Immunome’s Dr. Purnanand Sarma

Immunome CEO Purnanand Sarma, Ph.D. joins the Business of Biotech for a discussion on precision antibodies and his company’s discovery platform, which identifies novel therapeutic

A Network And Pivot Model For Success In Cancer Drug Development

When CEO Avanish Vellanki founded and incorporated Rain Therapeutics on his living room couch in the spring of 2017, there was no drug in development, no money, and a team of only four people. Five years later, after halting the development of its first licensed product, the Newark, CA-based precision oncology company awaits topline results from a pivotal Phase 3 trial in liposarcoma, which could open the door to a cancer therapy — milademetan — capable of treating as many as half of all known cancer types.

Improved Formulations to Enable Stable Delivery of Biologics

Thin-film freezing (TFF) is an advanced formulation process that can produce stable protein particles of submicron size and is potentially ideal for overcoming some of the challenges described above

biospace

Beyond Increments: Black Perspectives on Representation in the Life Sciences

“Like the ongoing activities that financial institutions have adopted regarding [their] intentional efforts to be inclusive, the life sciences industry may want to adopt similar approaches to increase the awareness of career opportunities within the field.