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Cytokine players keep the faith

But he hopes that Sotio will prevail by focusing on patients who have previously failed checkpoint inhibitors and cancers in which these drugs have not worked.

Biotech Startup Cerevance Strikes Alzheimer’s Research Deal With Merck

Biotechnology startup Cerevance Inc. could earn more than $1 billion through a collaboration with drugmaker Merck & Co. to research potential treatments for Alzheimer’s disease.

pharmavoice

Turning harp seal contraceptives into a ‘new genre’ of cancer treatments

With Andrew Hall at its helm, IMV has evolved an animal contraceptive into a unique drug delivery platform aimed at creating targeted cancer immunotherapies for humans.

Fierce-Biotech

Merck is back in Alzheimer’s saddle with $1B+ Cerevance pact, years after dropping the BACE

Cerevance is a central nervous system disorders-focused biotech backed by Bill Gates. Its main program so far has been the Parkinson’s disease therapy CVN424, which

endpoints

UPDATED: Merck makes first big splash for Alzheimer’s drug R&D since 2017 fail, inking research pact with Cerevance

For the first time since discontinuing its late-stage Alzheimer’s program, Merck has found promise on the path forward in the memory-robbing disease.

Drug Discovery

MindMed launches Phase 2b to study LSD in generalized anxiety disorder

Psychedelic medicine firm MindMed (Nasdaq: MNMD)has dosed the first patient in a Phase 2b dose-optimization trial of MM-120, a pharmaceutically optimized form of lysergic acid diethylamide (LSD).

cancer_network

Nicholas Coupe, MBBS, PhD, Provides Update on Phase 2 Study of IMM60 in Advanced Melanoma/NSCLC

PORT-2 is an activator of this population. It has direct impact against tumors in terms of upregulating PD-L1 expression, which we know is favorable because it can

The Bio Report

Using Gene Therapies to Treat Chronic, Inflammatory Conditions

A broad range of serious diseases involve chronic inflammation, which causes both pain and progressive damage. Xalud Therapeutics is developing a locally-delivered, non-viral gene therapy that is designed to harness the ability of interleukin-10 to regulate the immune system and restore homeostasis. The company’s lead indication is in osteoarthritis We spoke to Diem Nguyen, CEO of Xalud, about the role inteleukin-10 plays in regulating multiple pathways in the immune system, Xalud’s gene therapy, and the indications the company is pursuing.