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biospace

Aadi, SOTIO and Ikena Target Cancer-Causing Mutations at AACR  

SOTIO, a biotech company based in Prague and Cambridge, MA, focuses on improving CAR-T therapies and stable antibody-drug conjugates (ADCs). In its poster presentation, SOTIO announced preclinical data on its immunocytokine SOT201 and the BOXR CAR-T cell therapy BOXR1030. The company’s focus, however, was on its oral presentation featuring SOT101. 

BioProcessOnline

Commensal Viral Vectors With Ring Therapeutics’ Tuyen Ong, M.D.

Today, he’s CEO of Ring Therapeutics, a promising emerging biotech backed by Flagship Pioneering

Biosion grants Pyxis Oncology global rights to cancer drug in $232.5M deal

Biosion Inc. has out-licensed ex-China rights for its anti-Siglec-15 monoclonal antibody BSI-060T and additional preclinical assets with the same target to Pyxis Oncology Inc. for $10 million up front and potential milestone payments of up to $222.5 million, plus single to low double-digit royalties on commercial sales.

biospace

With Positive Phase II Results, Cerevance Proves Concept in Parkinson’s

Private drug discovery company Cerevance reported positive clinical trial results Thursday for CVN424, an experimental treatment for Parkinson’s disease. The drug was discovered using Cerevance’s NETSseq platform, which holds potential for Parkinson’s treatments as well as many other diseases caused by transcriptional genetic errors.

endpoints

Inside the race to make psychedelics ‘mainstream medicines’

When Berra Yazar-Klosinski was wrapping up her PhD in molecular cell and developmental biology at UC Santa Cruz, there was an unassuming little office right down the road, hidden inside a bungalow-style house with a postage-square lawn.

Biotech Startup Fundraising Has Been Resilient, But Investors Are Selective

Venture-capital investment in the biotechnology sector has proved to be resilient so far this year, despite stock-market turbulence and the slower pace of initial public offerings.

PRECISION MEDICINE FOR MENTAL ILLNESS

Alto Neuroscience wants to use EEG brain biomarkers to better match the right treatment to a person’s needs.

biospace

Running the Evolutionary Race against Microbes and Time in AMR

Entasis, which focuses on developing new antibacterial drugs to treat pathogens, utilizes a precision medicine approach to design specific drugs to target specific bacteria.