- | TFF Pharmaceuticals
From Zero to Hero: Biopharma’s Pivotal Inflection Point
As Glenn Mattes, CEO of TFF Pharmaceuticals, told BioSpace, “The persistent rise of COVID-19 cases, including among the vaccinated, has understandably impacted the morale of both the biopharma industry and the broader community.”
- | MeiraGTx
MeiraGTx Gets $30M Milestone Payment From Janssen Pharmaceuticals
MeiraGTx Holdings PLC said it received a $30 million payment from Janssen Pharmaceuticals Inc., part of the Janssen Pharmaceutical Cos. of Johnson & Johnson, for a clinical milestone in a Phase 3 trial of botaretigene sparoparvovec.
- | MindMed
FDA Clears Phase 2B Study Testing LSD for Anxiety
The US Food and Drug Administration has cleared an Investigational New Drug application allowing MindMed to move forward with a phase 2b dose-optimization trial of MM-120 for the treatment of generalized anxiety disorder (GAD).
- | TFF Pharmaceuticals
The Limitless Potential of Thin Film Freezing
To address both of these challenges, TFF Pharmaceuticals has developed a process called Thin Film Freezing (TFF), which produces drugs that are highly soluble and stable in a powder form, for a variety of applications, including delivery to the lung.
- | Recce Pharmaceuticals
A Perfect Storm of Superbugs
Recce’s lead drug candidate, called R327, is a synthetic polymer that is currently undergoing Phase I trials for sepsis, with an ongoing Phase I/II trial for burn wound infections. According to Graham, R327 utilizes multiple inhibitory mechanisms that work in “a synergistic compounding fashion.” These mechanisms include adenosine triphosphate (ATP) inhibition, cell membrane permeabilization and bacterial cell division inhibition.
- | Anixa Biosciences
Oh, Where Vaccines Could Take Us
San Jose-based Anixa Biosciences is looking to keep “retired” proteins from coming back and causing havoc to the body—particularly in the form of triple-negative breast cancer and ovarian cancer.
- | Canary Medical
Surprising Parts of the Body You Need to Exercise Regularly
You also need to be strong in other parts of your body if you want to keep active. In your knees, you need to maintain strength, but also flexibility and muscular balance, says Fred Cushner, M.D., an orthopedic surgeon at the Hospital for Special Surgery in New York City and chief medical officer for Canary Medical.
- | Renovacor
Precision Gene Therapy on the Cusp
Another company, Renovacor, is looking beyond oncology to cardiology – specifically to dilated cardiomyopathy. Its precision gene replacement therapy targets patients with mutations in the BAG3 gene that causes lower levels of BAG3 in the heart. “We want to boost levels of BAG3 in the heart to address the root cause of this aggressive disease,” Matt Killeen, Ph.D., CSO, told BioSpace.
