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GEN

Cell-Type-Specific Analyses
Guide Efforts against Brain Disease

Cerevance is working to change that. Proprietary
technology that accurately determines brain age and
relates it to Alzheimer’s, Parkinson’s, and other brain
diseases is providing novel insights that inform therapeutic development

GEN

Epigenetic Therapies Start Operating Outside the Lines

Durect focuses on eliminating the epigenetic faults that cause cells to become dysfunctional. Following this approach, Durect intends to generate drugs that can treat acute organ injury and chronic liver diseases.

Fierce-Biotech

Little European biotech Sotio nabs a super $316M funding round for its superagonist work

Sotio is also working on earlier efforts, including BOXR1030, its next-gen CAR-T program for solid tumors expressing GPC3 and based on its so-called BOXR platform “that aims to enhance the fitness of T cells in the hostile tumor microenvironment,” according to the Prague-based company.

Rare disease with fatal diagnosis doesn’t stop this woman from living life – and helping others

Last month, Jessie Jackson’s friends and family sang her happy birthday a little early. Jessie doesn’t turn 30 until Dec. 12, but for the past five years on the anniversary of her diagnosis, her parents have hosted a fundraiser. They weren’t taking any chances.

Seeking Alpha

BeyondSpring CEO Dr. Lan Huang – Targeting Cancer (Video)

BeyondSpring is a clinical stage biopharma focused on immuno-oncology cancer therapies. It developed Plinabulin for chemotherapy-induced neutropenia and non-small cell lung cancer. CEO and co-founder Dr. Lan Huang, a structural biologist by training, joined us to discuss Q4 milestones, the potential for Plinabulin, industry trends, 2022 outlook and why small molecule therapy is never going to go away.

Fierce-Biotech

Pfizer doles out $15M to Cardiff to advance a challenger to Amgen’s KRAS winner Lumakras

Pfizer must have liked what it saw in data presented by Cardiff Oncology for a challenger in KRAS-mutated cancers. The Big Pharma is putting up a $15 million equity investment in the biotech to help bankroll development of the drug. 

Longevity Technology

Fountain’s $15m to “restore youthful resilience to cells”

“Fountain is an example of a biotech company emerging as a direct result of basic research, in this case the biology of aging,” said Dr Rando, founder and chairman of Fountain. “The company’s screening and discovery platform is built upon foundational research showing that the age of a cell can be modulated by factors in the cell’s environment. By identifying compounds that work through these pathways, we seek to restore youthful resilience to cells and tissues, leading to therapies that treat or even prevent chronic diseases of aging.”

endpoints

The renowned drug hunter, the Washington insider, the MIT strategist: How did one low-profile biotech enlist a dream team of top biotech advisors?

When you’re heading up a fledgling biotech out to make a name for yourself in the middle of a wild industry boom, there’s one sure way to differentiate yourself that’s bound to attract universal nods.