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HQ Move Fuels Fountain’s AI Drug Discovery Machine

Fountain Therapeutics’ unique AI discovery platform prompted an invitation from Eli Lilly & Company to move Fountain headquarters to Lilly Gateway Labs. Company CEO Dr. John Dimos is making the most of it. 

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SMA, NMOSD and Aging – From Few to Everyone

Moira speaks with Dr. Levi Garraway, the Chief Medical Officer of Genentech about FDA approvals for treatments in two very rare diseases – SMA – Spinal Muscular Atrophy, and NMOSD – Neuromyelitis Optica Spectrum Disorder.

Scynexis submits NDA for oral ibrexafungerp for vaginal yeast infection

Scynexis announced today that it has submitted a new drug application to the FDA for oral ibrexafungerp for the treatment of vulvovaginal candidiasis, the second most common cause of vaginitis.

Mark Erlander of Cardiff Oncology, Inc. Discusses KRAS Mutations in Cancer

Mark Erlander, Chief Executive Officer at Cardiff Oncology, Inc. talks KRAS mutations in cancer, and existing products like mCRC, mCRPc and AML, along with three clinical programs including Zytiga-Resistant Metastatic Castration Resistant Prostate cancer (mCRPC); KRAS mutated Metastatic Colorectal Cancer (mCRC) and Relapsed/Refractory Acute Myeloid Leukemia (AML). You can find out more here.

Antiviral Conjugates – A Novel Treatment and Prevention Strategy for Viral Diseases Including COVID-19

Cidara Therapeutics has adopted key immuno-oncology principles and applied them to infectious disease, enabling the creation of a novel antiviral strategy – antiviral conjugates (AVCs). AVCs are long-acting, bispecific drugs that directly inhibit viral proliferation, whilst simultaneously

Oral coronavirus vaccine candidate enters clinical trial

An oral coronavirus vaccine candidate has entered the clinical trial phase, bringing with it a possible option for those wary of needles. Vaxart Inc. announced on Tuesday that the first subject had received a dose of the VXA-CoV2-1 oral tablet in a Phase 1 clinical trial.

Developing Novel Treatments for CNS Diseases

Technology Networks recently spoke with Brad Margus, CEO at Cerevance, to find out how the company is addressing key drug development challenges. In this industry insight, Margus tells us more about the company’s drug development pipeline and their lead candidate CVN424, which is currently being developed to treat Parkinson’s disease. He also explains how Cerevance’s Nuclear Enriched Transcript Sort sequencing (NETSseq) platform is helping to discover promising targets that could be exploited therapeutically.

San Diego biotechs have plunged into the fight against COVID-19. Here’s what they’re doing

Some of this work has already arrived, such as Helix’s COVID-19 test, which detects the coronavirus in thousands of samples collected at San Diego County test sites. Other efforts are several months away, including CalciMedica’s anti-inflammatory drug meant to help keep COVID-19 patients off ventilators; the biotech believes the treatment could be approved by May or June 2021, depending on data from ongoing trials.