
- | Vaccinex
Treating Huntington’s Disease by Addressing Neuroinflammation
Huntington’s disease is a rare and fatal neurodegenerative condition that is without any disease-modifying therapies today. Vaccinex is developing an experimental therapy designed to treat Huntington’s disease by addressing neuroinflammation, a hallmark of the condition that it shares with other neurodegenerative diseases.

- | NantKwest
Former Sen. Harry Reid Says He’s in ‘Complete Remission’ After Pancreatic Cancer Treatment
Dr. Soon-Shiong tells PEOPLE he’s working to create a more universal cancer treatment by rethinking how we use radiation to target cancer cells – and that Reid is proof it can work. Instead of blasting the body with high doses of radiation, the doctor says the method he’s testing “tickles” the cancer cells to wake them up, while at the same time a patient is injected with additional “natural killer cells” that reinforce the body’s immune system in order to find and fight off the cancer.

- | Cerevance
Will We Ever Find a Cure for Dementia?
This precise approach “makes it possible to make drugs that only act on the cell type you care about,” reducing the unwanted side effects that most drugs have, says Margus, chief executive officer of Cerevance, a Boston-based drug development company focused on brain diseases. What’s more, it could lead to a major breakthrough in the field of dementia research. About 50 million people worldwide suffer from dementia, and still there is no treatment to stop or slow its progression.

- | NeuroRx
New emergency COVID-19 drug in testing phase excites South Florida doctors
Dr. Jonathan Javitt, the CEO of NeuroRx, said, “We’re talking to people who have critical COVID-19, with respiratory failure. That is people whose lungs have been affected by the COVID virus, such that their lungs don’t send oxygen properly to their bodies. Then the drug will be available at every hospital.”

- | Neubase Therapeutics
Winston-Salem woman raises awareness about Huntington’s disease
“It’s a chronic neurodegenerative process. Chronic just means it goes on very slowly over a long period of time,” said Friedlander, of NeuBase Therapeutics. Holder’s father is at the point in his diagnosis where he often forgets a pandemic is going on. Seeing people in masks scares him.

- | Redhill Biopharma
Yeliva see anything: Redhill calls out opaganib’s promise in COVID-19
Redhill Biopharma Ltd.’s chief operating officer, Gilead Raday, told BioWorld that the firm will build on positive results in severe COVID-19 patients with oral opaganib, a first-in-class sphingosine kinase-2 inhibitor that the company has branded Yeliva, and could seek emergency use authorization based on data due by year-end.

- | 9 Meters Biopharma
9 Meters Beats Corporate Competitors to Phase III Celiac Trials
9 Meters Biopharma’s program for celiac disease is among the most clinically advanced programs in development. With phase III trials underway and Fast Track designation from the FDA, “It’s, conservatively, at least one year ahead of everyone else’s,” John Temperato, president and CEO, told BioSpace.

- | Celyad
David Gilham on Single Vector Multiplexed shRNA Maintenance
David Edward Gilham of The University of Manchester discusses single vector multiplexed shRNA provides a non-gene edited strategy to concurrently knockdown the expression of multiple genes in CAR T cells presented at this year’s virtual ASCO.