BLOG

Rockefeller University, Cerevance Pursue Pooled Nuclei Sequencing to Target Brain Cell Types

A cell-targeting sequencing method developed at Rockefeller University is being used to find drug targets for neurological conditions such as Parkinson’s and Alzheimer’s diseases. Nuclear enriched transcript sort sequencings (NETSseq) is a sample preparation method that uses antibodies or RNA probes to latch on to the nuclei of pre-determined cells of interest, capturing pools of them for downstream transcriptome profiling or even chromatin accessibility profiling with next-generation sequencing.