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GEN

Tolerogenic Therapies Retrain the Immune System

COUR Pharmaceuticals’ emerging platform reprograms the immune system to address the root causes of autoimmune diseases

cell gene

Tessera Therapeutics Advances In Vivo Gene Therapy For SCD

Last year, Tessera Therapeutics’ CEO, Dr. Michael Severino, was my guest on Cell & Gene: The Podcast to discuss Gene Writing, the biotech’s genome

Chicago Area’s Life Sciences Scene Continues Making an Impression

Chicago Biomedical Consortium and COUR Pharmaceuticals executives share what makes the area a hot spot.

endpoints

With schizophrenia trial success, LB Pharmaceuticals thinks about Phase 3 and next funding

A private startup looking to bring an old schizophrenia drug class to the US has released new Phase 2 data and aims to start a …

Fierce-Biotech

LB Pharma’s twist on old Sanofi drug passes schizophrenia test, teeing up phase 3 push

LB Pharmaceuticals has shared top-line data from a phase 2 schizophrenia trial, touting results that offer early support for its vision and putting it on track to start a pivotal study around the end of the year.

psych

First Patient Dosed in Phase 3 Study of Psychedelic MM120 in Generalized Anxiety Disorder

MindMed announced the first patient had been dosed in the first-ever phase 3 trial of lysergic acid-diethylamide (LSD) for generalized anxiety disorder (GAD). MindMed is currently the furthest along in clinical trials exploring LSD as a treatment in multiple psychiatric indications, including major depressive disorder.

BioProcessOnline

Internalizing Nanoparticle Therapeutic Development

COUR Pharmaceuticals has been, as its newly-appointed President & CEO Dannielle Appelhans puts it, flying under the radar for a long time. COUR made a splash back in 2015, when it formed up around a biodegradable nanoparticle encapsulating gliadin proteins that proved to reverse the effects of gluten in animal models.

Biotech TV

Philadelphia based Interius BioTherapeutics recently dosed the first patient for its in vivo CAR therapy that edits T and NK cells in the body so they target CD20 positive cells in B-cell malignancies

V.P. of R&D Tim Culp describes the rationale for in vivo CAR programs, what the company will be watching for from a safety standpoint, the development path ahead, and competition.