Chikungunya Vaccine Candidate Delivered Excellent Study Results
Valneva chikungunya vaccine candidate VLA1553 was generally safe in all dose groups and the local tolerability profile was excellent.
FDA Approves Talicia To Treat Superbug Linked To Stomach Cancer
The FDA’s decision to approve Talicia could have far-reaching impact, as this bug infects millions of American adults a year and is one of the strongest known causes of stomach cancer. Talicia is a three-drug combination of omeprazole, a proton pump inhibitor, amoxicillin, a penicillin-class antibacterial, and rifabutin, a rifamycin antibacterial. It is indicated for the treatment of H. pylori infection in adults.
Tissue Donor Tuly Gonzalez’s Legacy Continues Through The 8 Lives She Impacted
Family and friends gathered at the University of Miami Life Science and Technology Park Wednesday morning to remember Tuly Gonzalez on what would have been her 32nd birthday. She died 11 years ago but the gathering was not just to remember her, but to also celebrate the lives she has impacted though her donation.
Novel therapy safe, effective in acute, severe alcoholic hepatitis
In this exclusive video from The Liver Meeting 2019, Tarek Hassanein, MD, FAASLD, professor of medicine at UC San Diego Health and medical director of Southern California GI and Liver Centers, discusses results of a phase 2a study, which demonstrated that DUR-928 was well-tolerated and effective in patients with acute alcoholic hepatitis.
AASLD: Durect’s alcoholic hepatitis med repairs liver, cuts mortality in phase 2
Hepatitis used to be the talk of the town at The Liver Meeting, the annual gathering of the American Association for the Study of Liver Diseases. These days, the conversation is turning to nonalcoholic steatohepatitis (NASH), but its cousin alcoholic hepatitis (AH) isn’t getting much attention. Durect is trying to change that.
First Results Out for Off-the-Shelf CAR-T Therapy in Solid Tumors
The interim results come from an ongoing phase I trial in patients with colorectal cancer. Of the 12 patients given Celyad’s CAR T-cell immunotherapy so far, six have seen their tumors shrink. The therapy has also shown no evidence of causing graft-versus-host disease, a condition where foreign immune cells attack the host body. Celyad’s CAR T-cell immunotherapy is aimed to overcome the drawbacks of CAR T-cell immunotherapies already in the market such as Kymriah and Yescarta.
Gene therapy for wet AMD ‘on the horizon’
In the OPTIC trial, patients with wet age-related macular degeneration who were treated with ADVM-022, an intravitreal gene therapy, did not require additional injections following treatment, according to a presenter at the American Academy of Ophthalmology annual meeting.
